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Wyeth Pharmaceuticals signs $400m deal with Progenics
Wyeth Pharmaceuticals signs $400m deal with Progenics
Date published: 30/12/2005
Wyeth
Pharmaceuticals and Progenics Pharmaceuticals have announced that they have
entered into an exclusive, worldwide agreement worth over $400 million for the
joint development and commercialisation of methylnaltrexone (MNTX) for the
treatment of opioid-induced side effects, including constipation and
post-operative bowel dysfunction.
Under the terms of the collaboration,
Wyeth receives worldwide rights to MNTX, and Progenics retains an option to
co-promote the product in the United States. The companies will collaborate on
the worldwide development of MNTX. The transaction includes an upfront payment
of $60 million to Progenics with as much as an additional $356.5 million
payable upon achievement of certain milestones.
"MNTX fits well within
our current portfolio and represents a broad treatment platform with multiple
products intended to address unmet medical needs in opioid-induced bowel
disorders," said Bernard Poussot, president of Wyeth Pharmaceuticals and
executive vice president, Wyeth
Currently, there are no therapies
approved to treat the side effects of opioids. These side effects often prevent
optimal pain control and may prolong hospitalisation.
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