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AstraZeneca makes first payment to Avanir
AstraZeneca makes first payment to Avanir
Date published: 04/01/2006
The US
drug developer Avanir Pharmaceuticals received its first $5 million payment
from AstraZeneca as early stage clinical trials on a new cholesterol drug have
commenced. The payment marks the first milestone met by Avanir in an agreement
made between the two companies in July last year to develop and commercialise
Reverse Cholesterol Transport (RCT) enhancing compounds for the treatment of
cardiovascular disease.
As a part of the agreement Avanir took an
upfront payment of $10 million and could be eligible to $330 million if further
milestones are met.
Avanir is currently developing the process of
Reverse Cholesterol Transport (RCT), where cholesterol can be removed from body
tissues into the liver and then to the gall bladder to be excreted. The payment
comes as the RCT drug AZD2479 has now entered Phase I of testing after the US
Food and Drug Administration gave the investigational new drug application
(IND).
Gunnar Olsson, vice-president of AstraZeneca, said: "We are
pleased that we successfully submitted the U.S. IND for AZD2479 in a timely
way. The FDA's allowance of the IND is recognition of effective high quality
work by the combined Avanir-AstraZeneca team."
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