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  Home | Subscribe | Advertise | Archive | Contact | Resources | Jobs | Directory Issue 003. 24/11/03.  
 
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PharmaForce
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PCC
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CD Sales Recruitment
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Guided Solutions
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Taylor Tomkins Britton
Call: 01628 488 533
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Seltek Consultants
Call: 01279 657716
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Advance Recruitment
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Scientific Staff
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UKPharm
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Adderley Featherstone
Call: 01937 841 402
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 Featured jobs
Clinical Service Advisor (CSA)
Lanarkshire
Tel: 01494 818000

Theatre Sales Executive (South East)
Theatre sales and orthopaedic representative required to cover half of the South East of the UK. Product portfolio includes, power tools, lights
Tel: 01628 488 533

RBM (South)
Tel: 0870 751 2238

Hospital Sales Specialists (Sth East / Sth Thames)
With integrity, energy and the stature to build positive customer relationships, you must be comfortable working within a clinical environment
Tel: 01937 841 402

Product Manager (UK)
Working from both the office and out in the field, you will be responsible for liasing closely with customers and solving technical queries, working
Tel: 0870 751 2238

Regional Sales Manager (Central Division)
Leading manufacturer of incontinence products requires RSM to cover central region responsible for 4 sales execs and a team of clinical advisors.
Tel: 01628 488 533

Sales Specialist (South Yorks and Trent)
Selling Oncology related Ethical and Medical products into NHS Trusts and Hospitals within the South Yorkshire and Trent area. Dealing with
Tel: 0870 751 2238

Associate Product Manager (Bedfordshire)
Tel: 01494 818000

Medical Sales Part Time (UK Nation-wide)
Part time medical sales representative required for Innovative CSO. Calling on GP's, Pharmacist's and Practice Nurses.
Tel: 0870 2410536

Healthcare Development Executive (Trent)
Tel: 01494 818000

Hospital Specialist (North London, Essex, Wiltshire)
Selling a range of market-leading ophthalmics pharmaceuticals to Ophthalmic Consultants in secondary care. The company is launching a brand new...
Tel: 0800 783 0920

Medical rep (York)
Developing core brands through selling to customers in primary and secondary care. Meeting sales and activity targets
Tel: 0870 240 3038

Product Specialist (S Wales, Part W Mids, S W)
You will sell the companies range of products into hospitals on territory, the majority of your time will be spent in theatre at the side of general...
Tel: 0800 783 0920

Medical Representative (Somerset & East Devon)
Tel: 01494 818000

NHS Liaison Representative (South London)
The role involves dealing at PCO / PCT level, negotiating & gaining endorsements for The products, as well as liaising with the hospital team & doing a...
Tel: 0800 783 0920

Regional Territory Manager (Southern)
Our client is a well established and reliable supplier of biomedical tools to research and industry. They are a responsible partner in all areas of...
Tel: 01953 453753

Territory Manager (Kent/Sussex) - Selling near patient blood glucose testing kits into primary and secondary care. Date posted: 14/11/03

Regional Account Manager - Dispensing (South East)
Immediate requirement for a Dispensing Practice Sales Specialist to cover the South East. You will demonstrate a track record of success within a...
Tel: 020 7242 4266

Medical Imaging (North Midlands)
Our client is a leading provider of medical imaging and diagnostic equipment to the NHS and private hospital market. A rare and exciting opportunity...
Tel: 020 8722 8200

P/Time Medical Sales (Suffolk :: Lincolnshire)
Part-time opportunities: Suffolk & Lincolnshire (+Nationwide) for experienced Medical Sales Professionals and Trainees. Lundbeck is the only...
Tel: 0870 241 0536

Product Specialist (South West London)
Urgently looking for a hospital specialist to cover London and the home counties.
Tel: 01483 243589

Sales Executive (Lincolnshire and Nottingh)
Market leading manufacturer of woundcare products requires a sales executive to sell products to Hospitals and GPs
Tel: 01628 488 533

Business Deveopment Executive (South East)
2003 sees the development of a Nation-wide team of ¡¥ Business Development Managers¡¦ whose role is to report directly to the RBM covering all PCOs...
Tel: 01844 202010

Hospital Specialist (South West)
Role Selling a range of market-leading ophthalmics pharmaceuticals to Ophthalmic Consultants in secondary care. The company is launching a...
Tel: 0800 783 0920
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NHS Local - November 2003
Local NHS News - an overview of interesting stories
from PCTs during the last month.
from Health Direction


Pharma NewsBytes - November 2003
Selected Pharmaceutical press releases
from LeadDiscovery [read]


Local NHS Intelligence - November 2003.
By Duncan Alexander of Health Direction
Blackburn with Darwen PCT - New Repeat Dispensing Scheme
The new system of repeat dispensing means that prescriptions can be dispensed in intervals by community pharmacists. The pharmacist can prepare prescriptions when convenient, and it's often easier for the patient to collect them from the pharmacy.
Brighton and Hove City PCT / Adur, Arun and Worthing PCT - Teaching Status
Joint Teaching status has been awarded to these two PCTs, together with a £370,000 grant. The neighbouring PCTs share similar demographics and a workforce, as well as difficult health challenges and a number of poor health issues.
Buckinghamshire Mental Health NHS Trust - Memory Clinic Pilot Project
The Memory Clinic opened on 10 September and is based at the John Hampden Unit. It is part of a 6-month pilot project and follows the success of an earlier scheme led by local practitioners, intended to raise awareness of the early symptoms of dementia.
Central Liverpool PCT - Cervical Screening Campaign
Central Liverpool PCT have been giving away free knickers in the city centre to encourage young women to have a cervical smear test. Four out of 10 Liverpool women aged between 25 and 29 haven't had an adequate smear test in the last 5 years.
Croydon PCT - NHS Mammography Suite in Local Department Store
Allders in Croydon now has an NHS Mammography Suite in store. The service is provided by the South West London Breast Screening Service (St George's Healthcare NHS Trust). The PCT hopes to establish a permanent screening site in Purley next year.
Professional Careers Consulting [web-site]

Are you a dynamic and successful Medical Sales Professional?
Does your customer focus and knowledge stand you apart from the crowd?
Are you are looking to further develop your career?

Call now on: 0870 240 3038 or click here to view our current opportunities
Eastbourne Downs PCT - Community Pharmacists/Medicines Management Trial
Community Pharmacists are to be encouraged to contact GPs more often to suggest prescription changes. Examples include dose optimisation, duplication and cost-effective alternatives, and savings could mount to £30k per year. [click here to read more]
Fareham and Gosport PCT - Community Pharmacy Service
The PCT's Community Pharmacy Service visits patients at home, and the pharmacist removes medicines which are out of date or no longer required. This service is to be extended to all elderly patients discharged from hospital with more than 3 medications.
Harlow PCT - Waiting List Reduction for Vasectomy
Harlow PCT has reduced the vasectomy waiting list by two-thirds by moving the service into primary care from the hospital and keeping in touch with patients. One afternoon a week was set by at a local practice's operating room with a GP from a nearby PCT. [click here to read more]
High Peak and Dales - 48-Hour Access Target
Dr Peter Holden of the Matlock Surgery is among those doctors whose surgeries no longer offer pre-booked appointments in order to to ensure that every patient who requests an appointment can be seen within the 48-hour NHS target. [click here to read more]
Ipswich Hospital NHS Trust - COPD Pilot
The new Outreach Respiratory Team at Ipswich Hospital NHS Trust will support people with chronic respiratory problems in their own homes, after being discharged from hospital. This is a whole protocol of care for people with COPD and is a six-month pilot. [click here to read more]
London - The Big Smoke Debate
The Big Smoke Debate is run by London Health Commission. It is asking people who live and work in London for their opinions on passive smoking - WHERE smoking should occur rather than IF it should - and is the biggest consultation of its kind in the UK.
Mersey Care NHS Trust - New Asperger's Team
Asperger's syndrome is a variant of Autism, and this is the first health-funded Asperger's Team in the country. The multi-disciplinary team is based at Olive Mount Hospital, Wavertree and will, initially, only be available to people in the Liverpool area.
North Bradford PCT - Health Service Journal Award
After winning the Primary Care category at this year's HSJ awards, North Bradford PCT went on to win the overall award, the Prime Minister's Award for Excellence in Healthcare Management, with their project on primary care performance improvement.
Nottingham City PCT - MRSA Training Session for GPs
Nottingham City PCT has organised training courses on infection control for GPs and Practice Nurses in a bid to combat the growth of MRSA in general practice. The courses are aimed primarily at nurses who often deal with dressings and wounds. [click here to read more]
Rushcliffe PCT - Cancer Register Pilot
A Cancer Strategy Group has been formed at Rushcliffe PCT, and a Cancer Forum is planned. GP practices have also been invited to join local trials of a Primary Care Cancer Register.
Rushcliffe PCT - Diabetes Forum
The new Diabetes Forum has been set up so that interested local people can discuss their experiences and help to improve services. The first meeting will feature talks from the Director of Public Health, a representative from Diabetes UK and a local GP.
South Liverpool PCT - Head of Learning and Development
Angela Delea has been appointed Head of Learning and Development. She will take responsibility for the training and development of all staff at South, Central and North Liverpool PCTs as well as some staff at South Sefton PCT.
South London PCTs / South London HIV Partnership - New Range of Services
A new range of HIV Support Services were due to start in October, following a detailed needs assessment of service provision. Groups which have been targeted include women, African communities, children and young people. [click here to read more]
Southport and Formby PCT - Lymphoedema Specialist Nurse
Vicky Hindley, the new Lymphoedema Specialist Nurse at the PCT, will be working in the community as well as at the local hospital and hospice. She hopes to develop the service, and set up new clinics in Church Street (Southport) and in West Lancashire.

2nd Annual Sales Force Effectiveness Conference [website]

Eyeforpharma's 2nd Annual Sales Force Effectiveness Conference will tackle the hottest issues challenging your company both now and in the future! Already experiencing fantastic success from this years event, eyeforpharma are extremely positive that by attending this major calendar event, in just two fact filled days you can get to grips with the key strategies that will increase your bottom line and make your sales force dramatically more effective.

For further information: email or telephone +44 (0) 20 73 75 75 75.
Website: www.eyeforpharma.com/sales2004/.

Sutton and Merton PCT - Award
Annie Hoile is a Specialist HIV Nurse whose work also covers Richmond and Twickenham PCT and Wandsworth PCT. She has won an excellence award from the South West London SHA for the specialist HIV Nursing Service she set up 14 years ago.
United Lincolnshire Hospitals NHS Trust - Cancer/Palliative Care
Kathy Blythe is the new Macmillan Lead Nurse at Lincoln County Hospital. Part of her remit is to extend the cancer care services the county's GP surgeries. It is hoped that a new Palliative Care GP and Palliative Care Nurse will soon be appointed. [click here to read more]
Wandsworth PCT - Award
South West London SHA has presented a series of local NHS Excellence awards. The reception team at The Surgery, Queenstown Road, Battersea have developed their roles so that five can perform initial interviews and two are trained phlebotomists.
About the author

Health Direction Ltd is entirely focused on collecting, processing and analysing high quality UK-based health information for dissemination through intuitive, browser-based products via the internet, company intranet and CD-Rom. Privately owned and run you will find our staff friendly, knowledgeable and helpful. We put customer satisfaction at the top of our agenda.

If you have a requirement for NHS information, contact Health Direction.


Pharma NewsBytes - November 2003
Selected Pharmaceutical press releases from LeadDiscovery

The battle for the anti-hyperlipidemia market

In October AstraZeneca announced early figures concerning the sale of Crestor following its US launch in September . Although positive, these were put in context nn November 12th when Pfizer released clinical data on Lipitor, Crestor's biggest competitor and indeed the world's top-selling medicine. The Pfizer study, "The Reversing Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) study" presented at the annual meeting of the American Heart Association followed 502 patients, who were diagnosed with coronary heart disease and required cardiac catheterization, or angiograms. Patients in the 18-month study had at least one arterial vessel with 20 percent or more constriction due to plaque build up. The study compared the effectiveness of Lipitor (80 mg/day) versus Pravachol (40 mg/day) in reducing plaque build-up. Lipitor-treated patients experienced a median 0.4% reduction in total plaque volume. "These results clearly show that aggressively lowering cholesterol levels with atorvastatin calcium stopped the progression of atherosclerosis," said Dr. Steve Nissen, Medical Director of the Cleveland Clinic Cardiovascular Coordinating Center and Principal Investigator of the REVERSAL study. "This study further demonstrates the benefits of aggressively managing cholesterol levels to reduce the risk of atherosclerosis" [news article]

Recent surges in rheumatoid arthritis development activity

October/November proved to be big in rheumatoid arthritis news, coinciding with the Annual American College of Rheumatology meeting. LeadDiscovery's recent state of the art analysis of emerging rheumatoid arthritis therapeutics evaluates many of the new molecular targets for this disease (click here), one of which is the MCP-1/CCR2 chemokine pathway. On October 14th Millennium announced the initiation of a multicenter phase II clinical trial of MLN1202, their novel humanized monoclonal antibody which is specifically designed to block this pathway. Primary objectives of this double-blind, placebo-controlled, multiple dose-escalation study in approximately 30 patients with rheumatoid arthritis are to assess the safety, tolerability, pharmacokinetic, pharmacodynamic properties and biological activity of MLN1202 via synovial biopsy. The study will be conducted in Europe and Australia. A phase I single dose-escalation study was initiated in December 2002 to evaluate the tolerability, pharmacokinetic and pharmacodynamic effects of MLN1202 in healthy volunteers. MLN1202 was well tolerated and no drug-related serious adverse events were reported among the 48 volunteers in that study. In that study, MLN1202 also demonstrated predictable dose-dependent pharmacokinetics and significant blockade of the MCP-1/CCR2 pathway. "Our confidence in the initial data we have reviewed has encouraged us to move MLN1202 rapidly into phase II trials, only nine months after the initiation of the phase I trial," said Arthur Hiller, vice president, global strategic marketing at Millennium. "Rheumatoid arthritis remains a significant area of unmet medical need and we are hopeful that MLN1202's novel mechanism of action may someday provide patients with a new treatment option". The MCP-1/CCR2 pathway plays a central role in the pathogenic inflammatory response cycle of cell signaling, activation and amplification of inflammation. CCR2 receptors are found on the surface of monocytes, macrophages and T-cells and bind monocyte chemoattractant proteins (MCPs). By binding to the CCR2 receptor, MCPs signal monocytes and T-cells to migrate to sites of injury as part of the inflammatory process. MLN1202 is designed to specifically block the MCP-1/CCR2 chemokine pathway and prevent infiltration of immune cells into inflammatory sites, such as arthritic joints [news article].

Depressing news for anti-depressants

Following on from the adverse effect reported for Merck & Co's Vioxx (see above), the US drug giants run of dissappointing news continued with an announcement that it is discontinuing its Phase III clinical development program for its NK1 receptor antagonist, MK-0869, for the treatment of depression. The Phase III clinical program was halted because the compound failed to demonstrate efficacy for the treatment of depression. "There are significant challenges in scientific research, and unfortunately, sometimes disappointments," said Peter S. Kim, Ph.D., president, Merck Research Laboratories. "While we had reason to believe that the compound could be effective in the treatment of depression, the results of the Phase III trials did not demonstrate efficacy. Although Merck will not be continuing its clinical development program for MK-0869 in depression, we remain committed to our neuroscience research programs at our facilities in the United States and the United Kingdom," he said [news article].
About the author

LeadDiscovery offers a unique combination of technology mining and target discovery, on-line technology transfer and drug development, our aim is to feed pharmaceutical pipe-lines through the identification of exploitable research or academic/biotech partners. Our free DailyUpdates service provides daily publication tracking for the drug discovery community.

If you have a requirement for drug discovery information, contact LeadDiscovery
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